The RD must evaluate possible drug-induced nutrient deficiencies resulting from psychopharmacologic agents (eg, calcium intake due to selective serotonin reuptake inhibitors).26 Both conventional and functional laboratory tests can identify nutrient shortfalls and may include methylation genetic polymorphisms (eg, MTHFR, CBS, COMT), complete blood count, iron profile, and red blood cell vitamin, mineral, and fatty acid levels
Peer review Peer review information Nature Reviews Rheumatology thanks Devaraj Ezhilarasan, Shunsuke Mori and the other, anonymous, reviewer for their contribution to the peer review of this work
UVvis spectra were acquired using a Multiskan SkyHigh microplate spectrophotometer (ThermoFisher Scientific) and 96-well plates (Corning) or quartz cuvettes using SkanIt software
R-ALA is the biologically active form of ALA