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Carnitine participates in cell volume and fluid balancing in all tissues that are affected by the tonicity (iso-, hyper- hypo- tonicity) of the extracellular environment [19]
This intensive initial treatment rapidly replenishes depleted B12 stores and addresses acute symptoms
But the TMLHE gene is required for carnitine synthesis, so a mutation in this gene can lead to carnitine deficiency
En personas con enfermedad renal o heptica, la suplementacin puede no ser adecuada, ya que estos rganos estn involucrados en la sntesis y eliminacin de la carnitina, pudiendo acumularse a niveles perjudiciales
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