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Because PT-141 acts directly on the nervous system and the brains melanocortin receptors, rather than peripheral blood flow, it can address the root neurological drivers of sexual desire and arousal, offering a fundamentally different option for women whose symptoms persist despite conventional treatments

GLP-1 RAs lower fasting insulin and improve HOMA-IR indices, thereby decreasing circulating androgens and promoting follicular maturation

GLP-1RA use not associated with more hospitalizations for diabetic ketoacidosis or severe hypoglycemia

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