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Thirst isnt always a reliable way to tell if you are drinking enough liquids when using GLP-1s

In some cases, your insurance provider may also require you to do step therapy, which is a requirement for you to try and fail treatment effects with a different and less expensive medication first

That caveat matters when people ask me "is retatrutide actually better than tirzepatide?" The honest answer is: the single-arm Phase 3 efficacy numbers are larger, but we do not have the direct comparison yet