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The practical takeaway is that high-polyphenol EVOO is best understood as a metabolic tool within a whole-diet context, not as a standalone weight-loss agent

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Berberine is a potential therapeutic agent for metabolic syndrome via brown adipose tissue activation and metabolism regulation

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It has been investigated in research settings for its involvement in energy homeostasis, insulin sensitivity pathways, and stress-response signaling mechanisms

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166,167,168 The expression of HSPA5 increases in bladder cancer and correlates with patient prognosis

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