doi: 10.1097/01.shk.0000239764.80033.7e 190 LeeTHJawanBChouWYLuCNWuCLKuoHMet al
Safety Endpoints in Research Multiple clinical studies have confirmed the safety of both L-citrulline and glutathione, with no significant adverse effects reported when used as directed: Hwang et al
M., Higashiguchi, S., Horie, K., et al
As a supplement, it may help with symptoms of flu, chronic bronchitis, and COPD symptoms, but evidence is weak for its purported ability to thin mucus during a cold and general claims of "immune support." Very preliminary studies suggest benefits for polycystic ovary syndrome (PCOS), Sjogrens syndrome, schizophrenia, compulsive behavior, as well as anti-aging applications (see What It Does)