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Ipamorelin is a selective ghrelin receptor agonist that stimulates GH release through a complementary pathway without producing the cortisol and ACTH elevation seen with older secretagogues

Indirect Effects: Gastrointestinal issues, such as nausea and vomiting caused by semaglutide, could lead to muscle strain, including back pain

doi: 10.3389/fnbeh.2026.1805953 Received 06 February 2026 Revised 13 March 2026 Accepted 13 March 2026 Published 13 April 2026 Volume 20 - 2026 Edited by Emmanuel Darcq, Institut National de la Sant et de la Recherche Mdicale (INSERM), France Reviewed by Zhe Zhao, Max Planck Florida Institute for Neuroscience (MPFI), United States Madhawi Aldhwayan, King Saud University, Saudi Arabia Updates Copyright 2026 OConnor

Once prescribed this medication, users will start on a small dose and gradually increase the amount until reaching the maximum dose