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Recommended dosing of 1-2 mg subcutaneous injection 2-3x per week (6 mg/week total) compares to toxic dose estimated at ~22,500 mg (approximately 3,750 times higher than weekly dose)
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Tirzepatides insulinotropic effects on human islets depend on GIPR activity, according to Ei et al
Our previously published work revealed that plasma ALC levels were lower in individuals with familial hypercholesterolemia (33)
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