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GLP-1 (glucagon-like peptide-1) is a hormone your body naturally produces that plays a role in appetite regulation, fullness, and blood sugar control
The exocrine pancreas has GLP-1 receptors, mainly on the acinar cells
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As the confounding structure for the head-to-head comparison of tirzepatide versus semaglutide was expected to be more similar to the tirzepatide versus dulaglutide benchmarking study, we proceeded with the prespecified analysis plan that included death in the primary composite MACE outcome
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