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95% CI, 0.80-0.90) and 80 years of age (aHR, 0.80

As we age, our glutathione production begins to slow, and cell damage amasses

With respect to dosage, the average reductions were: 2000 mcg: 71.5% (single data point) 1,000 mcg: 31.8% Although limited data are available for higher dosages, the findings support the efficacy of both oral and non-oral B12 formulations in modulating homocysteine levels

Dorne J, Cirlini M, Louisse J, Pedroni L, Galaverna G, Dellafiora L (2022) A computational understanding of inter-individual variability in CYP2D6 activity to investigate the impact of missense mutations on Ochratoxin A metabolism