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Combination therapies should be offered as a first line of treatment and not as a last resort for patients with severe and complex obesity
PMID: 11713213
4 Challenges and future directions 4.1 Safety considerations The safety profile of dual or triple receptor agonists targeting GLP-1, GIP, and GCG receptors in the treatment of MASLD and related metabolic disorders warrants careful evaluation
GSSG + Pt-SH PtS-SG + GSH Deficiency of reduced glutathione deprives the cell of its antioxidant reserve, making it more susceptible to the damaging effects of ROS [14]
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