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Quantitative (Descriptive) Synthesis Studies were categorized and summarized according to key dimensions: Study design (RCT, post hoc RCT analysis, observational comparative study) Population characteristics (diabetes type, CKD stage, overweight/obesity criteria) Intervention or exposure and comparator (drug, dose, route, active vs

The medication did not significantly improve fibrosis compared with placebo, but it did improve weight, lipids, and the diabetes metric HbA1c

Overexpression of IGF-1 in Muscle Attenuates Disease in a Mouse Model of Spinal and Bulbar Muscular Atrophy