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The mechanism of curcumin to protect mouse ovaries from oxidative damage by regulating AMPK/mTOR mediated autophagy

Introduction You may have heard glutathione described as the "master antioxidant" of the human body

An example is copper-dependent enzymes lysly oxidase (cross-links collagen and elastin to rebuild connective tissues), and superoxide dismutase (major antioxidant enzyme to protect against damage/aged cells), with both contributing to collagen formation, antioxidant defenses, and extracellular matrix rebuilding

For instance, furosemide can inhibit metabolic pathways modulated by several enzymes including UDP-glucuronyltransferases (Sorgel et al., 1980), 11-hydroxysteroid dehydrogenases (Escher et al., 1995