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These are typically mild and often decrease over time as your body adjusts

2.2 Chronic venous insufficiency Two RDP studies on chronic venous insufficiency have shown another interesting clinical application of Pycnogenol (32, 33) that can be mechanistically explained by its beneficial effects on endothelial function and its anti-inflammatory action (65)

Dietary modifications are often the first-line approach to managing stomach problems on Wegovy: Eat smaller, more frequent meals rather than large portions, as this reduces gastric distension and works with the delayed gastric emptying caused by semaglutide Avoid high-fat, greasy, or spicy foods , which can exacerbate nausea and slow digestion further Stay well hydrated , sipping water throughout the day, but avoid drinking large volumes with meals Limit alcohol and caffeine , both of which can irritate the gastric mucosa Avoid lying down immediately after eating

Any future Canadian authorization would follow a successful regulatory submission