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Individual response still varies, which is why a supervised, personalized plan matters
These medications can be highly effective, but as their use grows, physicians are seeing more patients experience gallbladder-related symptoms that may be linked to these therapies
That will require larger, dedicated randomized trials in addiction, targeted studies in pain syndromes beyond knee osteoarthritis, longer-term musculoskeletal safety data, and honest communication about both the promise and the risks of GLP-1s
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