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Not only did different animal models such as rats, mice, rabbits and hamsters, help in the discovery and understanding of the therapeutic pathway of GLP-1 drugs, but they also provided crucial data on drug safety, pharmacokinetics and organ-specific effects, all of which were necessary for achieving regulatory approval and the successful translation to human use
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In some cases, CPGs simply are relabeling existing products
Genetic evidence that -arrestins are dispensable for the initiation of 2-adrenergic receptor signaling to ERK
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