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The P values are from the Seurat Wilcoxon rank-sum test, and the adjusted P values are BenjaminiHochberg false discovery rate FDR-corrected P values

Tirzepatide is a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist used for chronic weight management, along with a reduced calorie diet and increased physical activity, for people with an initial body mass index (BMI) of: 30 kg/m2 or greater (obesity) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, dyslipidemia, obstructive sleep apnea or cardiovascular disease)

Niacin can also cause bloating, burping, facial redness, and increased gas

Front Endocrinol (Lausanne) 2022;13:863592.PubMedPMC 43

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