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13.3.5 Virulence trait expression and reversion risk Of particular concern in the safety evaluation of probiotics is their potential for virulence reversion, a risk that is markedly higher in strains of pathogenic origin, particularly under favorable environmental conditions

11 Figure 2: The likelihood of patients being diagnosed with depression after a GLP-1 prescription compared to those on a non-GLP-1 medication 11 Initial studies on the risk of suicide in individuals taking GLP-1s indicate that these drugs may increase suicidal thoughts and ideation