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All three residues play a much greater role in GLP-1 mediated cAMP signalling, relative to oxyntomodulin (Figs
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This study found that the insulin surge following the meal was blunted with the administration of the GLP-1 antagonist, suggesting that GLP-1 plays an important role in the exaggerated insulin response seen in post-prandial hypoglycemia in children who had undergone a fundoplication (42)
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