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Effect of dapagliflozin on the rate of decline in kidney function in patients with chronic kidney disease with and without type 2 diabetes: a prespecified analysis from the DAPA-CKD trial

Side Effects & Safety Profile: A Research Perspective Tesamorelin Side Effects Fluid retention/edema related to IGF-1 rise and sodium reabsorption Arthralgia (joint discomfort) common with elevated GH Glucose dysregulation potential insulin resistance at higher doses Injection site reactions redness, swelling at the subcutaneous administration site Rare: peripheral neuropathy, carpal tunnel symptoms in long protocols Sermorelin Side Effects Mild injection site irritation most common and typically transient Flushing or warmth at the injection site Rare: headache or dizziness post-injection Minimal systemic effects best-in-class safety profile among GHRH analogs Both peptides carry a theoretical risk of promoting insulin resistance at excessive GH levels a standard consideration in any GH-elevating research

Allergic reactions include: itching, eczema, urticaria, redness of the skin, edema can be severe, generalized malaise

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