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The molecule was first identified and studied by the Sikiric research group in Croatia starting in the early 1990s, and the bulk of the preclinical evidence base comes from more than three decades of rat and rodent studies showing consistent tissue-repair, anti-inflammatory, and gastroprotective effects
The Fc domain not only provides steric protection against proteolytic enzymes but may also reduce immunogenicity by minimizing the generation of anti-drug antibodies
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Neuroprotection Supports nerve regeneration and protects against neurotoxic damage
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