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Most people need to continue treatment long-term to maintain their weight loss
When activated, AMPK may enhance insulin sensitivity, increase glucose uptake in skeletal muscle, suppress hepatic gluconeogenesis, and improve lipid metabolism
These factors do not act in isolation
Patients experiencing persistent skin dryness, unusual texture changes, or delayed wound healing should discuss nutritional assessment with their healthcare provider, though a direct causal relationship between GLP-1 therapy and specific nutritional deficiencies has not been firmly established
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