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Its called ochronosis, and its characterized by areas of gray-blue or blue-black discoloration that are hard to treat or even permanent
Further reciprocal mutagenesis studies will be required to identify key interactions responsible for the contrasting effects of exendin-phe1, exendin-asp3 and other analogs, facilitating future design of agonists with even greater selectivity
B12 deficiency can occur for several reasons, including- Dietary Restrictions- People following strict vegetarian or vegan diets may not consume enough B12-rich foods, leading to deficiency
Circulation 103(2):207212
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