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These observations suggest a significant contribution of CYPOR to NFT-induced Nrf2 activation in the HepG2 model, but also indicate that other cellular flavoprotein reductases are likely to be involved in the formation of the NFT radical anion and its subsequent activation of Nrf2 and synthesis of GCLC and glutathione
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When you swallow a standard glutathione capsule, the enzymes in your stomach and intestines often break the tripeptide back down into its individual amino acids before it ever reaches your bloodstream
every row is unpacked, with citations, in the sections that follow
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