When Histamine Symptoms Extend Beyond Food A low-histamine diet may reduce meal-triggered symptoms, but it cannot by itself determine whether the patient has undermethylation, copper overload, pyroluria, mast-cell activation or another biochemical pattern
Persistent fatigue, brain fog, low mood, weight gain, tingling in the hands or feet, frequent illness, post-COVID fatigue, or feeling generally "off" despite eating well and sleeping enough, especially if you're vegetarian, vegan, over 50, on metformin or a long-term acid reflux medication, or have a history of low B12 or pernicious anemia
Sampliner, R
known trial-reported adverse effects include gastrointestinal symptoms, injection site reactions, increased heart rate, and hypoglycaemia risk