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Several technical reasons may explain our distinctive findings, including differences in the microbiome sampling site, the limited n per group, singly housing mice, or the use of highly similar lean, Western, and high-fat diets which systematically exchanged fat content with carbohydrate content
Additionally, the flavonoids found in fruits and vegetables, such as quercetin and curcumin, have been shown to support detoxification by increasing the activity of detoxification enzymes, including those involved in conjugation
Evaluation on liver enzymes revealed constitutive induction of CYP2E1 and ALDH1A1 in untreated GCLM KO mice
A number of viruses, such as HCV, HBV, IAV, and ZIKV, modulate the antioxidant defense system to produce ROS 32,49,50,51,52
