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1 Although the mechanism behind bitter hops effects is still unclear, the hypothesis is that gut-exposed bitterness (the activation of the bitter taste receptors in the digestive tract rather than on the tongue) may influence appetite signals through interactions with these peptide hormones

Medical supervision with emergency resuscitation equipment must remain available throughout infusion

Finally, as this review did not include a quantitative meta-analysis, the synthesis remains qualitative and is subject to interpretation

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