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Cycle Duration 52 weeks (26-week weight-loss + 26-week maintenance) Repeatable Single cycle Suggested Bloodwork (4 tests) DXA body composition scan When: Baseline and 26 weeks Why: Measure lean mass and fat mass changes CMP (Comprehensive Metabolic Panel) When: Baseline Why: Liver and kidney function baseline Lipid panel When: Baseline and 26 weeks Why: Monitor cardiovascular risk factors Anti-drug antibodies When: Periodic Why: Monitor for immunogenicity Key Considerations Investigational monoclonal antibody available only through clinical trials

Segn la etiqueta de la FDA, la dosis inicial es de 2.5 mg semanales durante 4 semanas como dosis de inicio para mejorar la tolerabilidad gastrointestinal

Lipids Additional Notes Administered via once-weekly subcutaneous injection in clinical trials

In the absence of comorbidities or identifiable risk factors, semaglutide-induced ischemic colitis appears the likely etiology