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Dihexa was developed specifically to be orally active and capable of crossing the blood-brain barrier, making it a practical candidate for neurological applications
The Michaelis constant of ChaC1 for GSH is ~2.20.4 mM (47), comparable with the concentration of intracellular GSH (1-10 mM) under physiological conditions
CellTox Green Cytotoxicity Assay performed prior to aspiration of medium for GSH/GSSG-Glo Assay
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