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Researchers have found that these preproglucagon neurons are naturally activated, specifically after large meals
[41] In a normal person at therapeutic doses, this effect is usually not noticeable, but when respiration is already compromised, it may be evident
Full collagen remodeling takes longer, typically 12 to 16 weeks
Additionally, there is a boxed warning regarding thyroid C-cell tumors based on rodent studies, though human relevance remains uncertain
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