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Glutathione also works with glutathione peroxidase, an antioxidant enzyme that helps convert hydrogen peroxide and lipid peroxides into less reactive substances
Greater weight loss during treatment was associated with greater rebound, suggesting biological adaptations, potentially involving changes in appetite hormones, metabolism, or reward sensitivitythat increase susceptibility to weight regain [141]
Second, this analysis focused exclusively on a subset of GLP-1 RA therapies (specifically semaglutide and tirzepatide) and did not account for other common PCOS treatments, such as metformin, combined oral contraceptives, or anti-androgen therapies
Table 5
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