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2017), PL 14736 and PL10 (Tkalevi et al

Animal studies and in vitro work predominate the literature

If the label says it contains B12 but the solution shows no color, either the B12 concentration is extremely low (possible but unusual), the B12 has degraded (possible if exposed to light), or there was a labeling error (possible at any pharmacy)

Human Evidence To Date Publicly available human data consist of a small 12 patient open label intravesical pilot in women with interstitial cystitis non responsive to prior therapy plus anecdotal or preliminary references to other ongoing studies without published results