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Upon reaching confluence, cultures were incubated with the adipogenesis induction cocktail (growth medium supplemented with 5 g ml 1 insulin, 1 M dexamethasone, 0.5 mM isobutylmethyxanthine and 1 M rosiglitazone) for day 12 of differentiation
Additionally, in a mouse model of ischemic stroke, administration of the prebiotic Puerariae Lobatae Radix-resistant starch (PLR-RS) improved neurological outcomes by restoring gut microbiota balance, enhancing gut barrier function, and increasing melatonin production
Clinical trials show measurable benefits including 29% cognitive improvement in Alzheimer's patients, faster COVID-19 recovery times, and 10% reduction in liver fat content
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