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Toxicology of glutathione transferases
Aging 35 ChemerinskiE.PetraccaG.TesnA.SabeL.LeiguardaR.StarksteinS
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This creates a vicious cyclemtROS accumulation M1 macrophage activation secondary ROS burst amplified mitochondrial injurythat accelerates tubular apoptosis and ferroptosis and contributes to maladaptive repair and fibrotic remodeling
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