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GLP-1 medications may not be appropriate for individuals with a personal or family history of medullary thyroid carcinoma or MEN2 syndrome, history of pancreatitis, pregnancy or breastfeeding, BMI under 27 without weight-related comorbidities, or those who haven't yet tried structured lifestyle changes
Sekhars years-long expertise, knowledge and interest in metabolic disorders affecting HIV patients and a parallel track investigating non-HIV people have resulted in the publication of significant discoveries regarding the metabolic complications in aging, HIV and diabetes, and has guided numerous clinical trials that together provide a better understanding of why we age
Lam AT et al
Rather than a drug-specific anomaly, they noted that these trends point to a broader therapeutic role for incretin-based therapies in ocular health, with tirzepatide potentially amplifying this benefit
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