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As necrosis is often associated with early damage of mitochondria that leads to disruption of cellular energy supply, function of mitochondria was probed with the fluorescent mitochondrial potential sensor TMRM
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EF-hand motifs The catalytic core of PLCs is composed of the EF-hand motifs, X and Y domains, and C2 domain (Rhee and Choi, 1992)
The analog prevented the decline of brain glucose consumption, but we found no effect on fibrillary A accumulation or cognition
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