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GSH also buffers toxic electrophiles and environmental toxins through conjugation reactions
Matsumura N, Kinoshita C, Bhadhprasit W, Nakaki T, Aoyama K (2023) A purine derivative, paraxanthine, promotes cysteine uptake for glutathione synthesis
Some investigations have demonstrated that the two compounds, acting as agonists of the GSH antioxidant system, well prevent oxidative stress and reduce heart damage in some animal cardiomyopathy models, for instance, the ISO-induced myocardium infarction model [159, 160]
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