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Marashly, [email protected] Specialty section: This article was submitted to Neurodegeneration, a section of the journal Frontiers in Neurology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Humans inhale an estimated 100-1,000 Aspergillus conidia daily, most of which are cleared by the mucociliary system of airway epithelial cells and resident alveolar macrophages (van de Veerdonk et al., 2017)

Subcutaneous, intramuscular, and even oral routes all show effect, though injectable routes generally show better uptake and more predictable results