Recently, it was reported that cell viability, adhesion, and trilineage differentiation potential can be preserved using a cryoprotection solution composed of 90% fetal bovine serum and 10% dimethyl sulfoxide ( 5 Issues to be addressed in the treatment of PH by MSCs MSCs have started to demonstrate therapeutic potential in clinical trials for diverse diseases, such as neurodegenerative ones (Rash et al., 2025), cardiovascular, and autoimmune diseases (Shan et al., 2024)
171 Additionally, small molecule drugs may have better tissue permeability, longer half-lives in the body, and lower production costs
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These fat compartments are architecturally significant because they define contour, so when they shrink, the overlying skin has nothing to drape over