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As GLP-1 medications, like Ozempic, continue to gain attention for their role in managing chronic conditions, HR and employee benefits professionals are increasingly fielding questions about coverageincluding for off-label uses like treating Polycystic Ovarian Syndrome (PCOS)

Osimertinib is a third-generation molecular targeted drug that acts as an EGFR TKI, designed to target both EGFR-sensitising and EGFR T790M resistance mutations

However, some scholars have proposed that the effect of GLP-1 in the liver is indirectly mediated by multiple mechanisms, such as reducing fat absorption or inhibiting fat cells through acyl-CoA synthetase long chain family member 1 (ACSL1), CCAAT/enhancer binding protein (C/EBP), peroxisome proliferator-activated receptor- (PPAR), and sterol regulatory element binding protein-1c (SREBP-1c) pathways to achieve the purpose of reducing liver lipids [38]

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