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At the most basic level, it functions by enhancing insulin responsiveness, minimizing glucose generation in the liver, and stimulating glucose uptake from the circulatory system

Use of the arginine-depleting agent pegylated arginine deiminase ADI-PEG20 in GBM can increase nitric oxide (NO) synthesis and produce cytotoxic pernitrite, increasing the sensitivity of tumor cells to ionizing radiation and significantly enhancing the effect of radiotherapy on GBM

There is strong research interest in the application of ipamorelin to improve athletic performance but no research currently exists to show how it may be dosed for this purpose [14]

Hepatology 46 , 13921403 (2007)