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Standard daily dose: 250 mcg total blend once daily for 4 weeks or longer

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Some researchers achieve their desired outcomes at 1.0mg or 1.7mg and stay there

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Journal of Physiology-Paris , 95 (16), 315324

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The peptides mechanism NNMT inhibition to increase NAD+ availability is physiologically sound, but sustained enzyme suppression over months or years has not been studied in clinical trials

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