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Glycemic and Extra-Glycemic Effectiveness Intraclass Comparisons Among GLP-1RAs As far as GLP-1RA treatments are concerned, few RCTs have tested different compounds in head-to-head comparisons, 2631 and often these types of comparison are described by means of network-meta-analyses (ie, using a common comparator as reference, although the studies are conducted in different populations) 3234 or as meta-regression

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However, delayed gastric emptying may affect absorption of oral medicines with narrow therapeutic indices, so individual assessment is important

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