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This is particularly beneficial for individuals with obesity, insulin resistance, or metabolic syndrome
The amino groups of GSH can be fully protonated and exhibit high positive charges at pH 1.2
Remarkably, however, it is still not understood why the glucagon response is deficient or even absent in individuals with type 1 diabetes (and long-standing type 2 diabetes [58]), where this deficient response appears to be independent of the presence or absence of autonomic neuropathy [59]
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