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Retatrutide is a synthetic 39-amino acid acylated peptide classified as a triple receptor agonist (GLP-1, GIP, and glucagon receptors), available as a lyophilized powder for laboratory research

It established two cohorts: 244,063 patients in the GLP-1 RA treatment group (Victoza, Saxenda, Ozempic, Wegovy) and 11,439,560 patients in the non-GLP-1 RA group

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