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NICE guidance emphasises the importance of investigating the underlying cause of B12 deficiency rather than simply treating with supplements, as this may identify serious conditions requiring specific management
Serious B12 deficiency may cause anemia and nerve damage
For shift workers, travelers, or people with irregular schedules, the minimum viable protocol is this: inject before your longest sleep period of the day, fasted for at least 90 minutes
S2CID 23493993
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