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For instance, doxorubicin, a topoisomerase inhibitor, induces DNA damage in cancer cells by interfering with topoisomerases and unwinding supercoiled DNA 24

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Ferroptosis, Cardiac Vulnerability, & Glutathione Dependency Beyond generalized oxidative injury, glutathione critically governs ferroptotic pathways, linking impaired redox control to cardiomyocyte loss and heightened vulnerability to ischemic and metabolic stress

Microchannels presence is confined to the superficial layers of the skin, where the blood vessels and nerve endings are absent, resulting in a reduction of discomfort