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& Vlaisavljevi, V
Study-defined categories for the index medication were monotherapy (only drug of interest initiated), combination therapy (simultaneous initiation with another drug of interest), add-on therapy (initiation in addition to existing drug of interest), switched-to therapy (replacement of drug of interest), simultaneous add-on and switched-to therapy, and nonevaluable index therapy
The key is to methodically change one condition at a timesolvent type, volume, temperature, timeand observe if the issue resolves
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