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Perhaps the best way to think of Glutathione is as your bodys frontline defence system, supporting the livers phase II detoxification pathways
Under conditions of oxidative damage, Kelch-like ECH-associated protein 1 (KEAP1) can dissociate from the NRF2-KEAP1 complex, thereby activating NRF2 to exert antioxidant functions [69] [Figure 2]
On the other hand, mice on a control diet with transgenic overexpression of FGF21 significantly increase ketogenesis in the fed state, consistent with enhanced fat oxidation (286)
ShahSHBainJRMuehlbauerMJStevensRDCrosslinDRHaynesCet al
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