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1 Originally FDA-approved for type 2 diabetes, GLP-1 RAs also lead to sustained weight loss and have revolutionized diabetes and obesity management
Its unclear whether or for how long compounded semaglutide products will remain on the market
The rate of payload release following internalization of such linkers varies, mainly related to substituents proximal to the pyrophosphate moiety, suggesting that the release rate can be controlled by designing different structures
Not all side effects are mild
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